The regulatory NodD proteins of Rhizobium bacteria mediate the activation of a gene set responsible for symbiotic nodule formation by plant signal molecules. Here we discuss the signal recognition and gene activation properties of NodD and present a model summarizing the current knowledge on NodD action.

"Whether we think history has a definite logic of its own, or is merely the emergent quality of an irreducible contingency – it is usually taken as granted that it the same way in all its course. This is the case with some philosophers who argue against a conception of history as having an inherent logic. In this paper I present Postone’s critical reexamination of Marxian categories and argue that based on his project, we can criticize the presupposition of the (...) “sameness” of history. For although there is no transhistorically valid “logic of history”, something like it is constituted by the functioning of capitalism’s elementary categories. Keywords: history, historical time, logic of history, capitalism, traditional Marxism, Moishe Postone". (shrink)

The paper explores Burke’s twofold solution to the paradox of negative emotions. His Philosophical Enquiry (1757/59) employs two models that stand on different anthropological principles: the Exercise Argument borrowed from authors like the Abbé Du Bos, guided by the principle of self-preservation, and the Sympathy Argument, propageted by notable men of lettres such as Lord Kames, ruled by the principle of sociability. Burke interlocks these two arguments through a teleologically-ordered physiology, in which the natural laws of the human body and (...) mind, secretly working in the depth of the nerve fibres, ensure both self-preservation and sociability. Utilizing both efficient and final causes throughout his Enquiry, Burke argues that the experiences of pain and terror – under certain conditions – are made agreeable (delight) by providence,so that the physiological mechanisms underlying these experiences could ensure the health and strenuousness of the nerve fibres amidst the corrupting pleasures of commercial society (Exercise Argument). Furthermore, due to the ambiguous character of this delight annexed to such experiences, they also function as exercises for our social passions (Sympathy Argument). Te 'egoistic' anthropological drive to remove the visceral uneasiness that dominates these experiences facilitates moral action when it is needed the most: when others in pain need our help. In accordance with the anthropocentric providentialism of the moderate Enlightenment, it is the design of the human frame that ensures the activities essential to our health (self-preservation) and moral conduct (sociability), a design that not only guarantees that pleasure, if exclusive and excessive, is 'inconvenient', and pain, if mitigated and harmless, is aesthetically agreeable, but also that our 'egoistic' drive to self-preservation ultimately improves sociability. (shrink)

György Alajos Szerdahely, the first professor of aesthetics in Pest, publishes his Aesthetica in 1778, a work, written in Latin, that not only engages with the eclectic university aesthetics of late-18th-century Germany and Central Europe, but also marks the beginning of the Hungarian aesthetic tradition. Szerdahely proposes aesthetics as the doctrine of taste, a philosophical discipline that can polish our manners and social conduct through a sensual-affective Bildung offered by art experiences. Highlighting his sources in both British criticism and (...) German aesthetics, the paper traces the development of Szerdahely's concept of beauty from beauty as form (uniformity amidst variety) to beauty in motion (sensibility). Initially, Szerdahely argues for unity and variety as the two main constituents of a beautiful object, evoking disinterested contemplation, but he then turns to sensibility as the third necessary condition of beauty: an object becomes aesthetically beautiful only if it has the power to strike the senses (Lux) and stir the affections (Vivacitas), enlivening the whole embodied person. The paper argues that this third principle of sensibility proves to be more emphatic than the first two, leading to (1) the aesthetic conception of beauty as an experiential quality; but more interestingly to (2) the incorporation of the element of self-preservation and self-love into aesthetic experience. The reason for the latter development lies in Szerdahely’s anthropological argument, which traces back every affection to the instantaneous apprehension of good or evil concerning ourselves, implying desire (Adpetitus) or aversion (Auersi) in our reactions. (shrink)

Adrian Vlot used a lot of information when he wrote his article. I do not intend this brief presentation to give additional information or remarks on the topic. My aim is to support his ideas. I am a mathematician, physicist and theologian. I interpret science as a human activity describing and understanding the phenomena of the created universe based on observation, explaining the relationships in the universe afterwards and, in addition, discovering further areas via human intellectual abilities. In my interpretation (...) technology is something through which man makes use of the experience, knowledge, discovered relationships and laws in practice to create new tools or new materials which facilitate further research. That is how science and technology are related. In historical chronology, technology preceded science but later science also achieved results preceding their application in practice. Among others, the chronological intertwining is represented by Faraday and Maxwell’s activities. (shrink)

Book review of Dadejík, O., Kaplický, M., Ševčík, M., and Zuska, V. (2021) Process and Aesthetics: An Outline of Whiteheadian Aesthetics and Beyond. Prague: Karolinum Press. ISBN 978-80-246-4726-5.

The paper is meant to introduce a symposium on aesthetics in Hungary today. Through a brief survey of the Hungarian aesthetic tradition, which goes back to the eclectic “university aesthetics” of the late 18 th century and produced a number of prominent figures such as Georg Lukács and his disciples in the “Budapest School” in the 20th century, the paper seeks to point out some key characteristics of this tradition and to reflect on the intellectual landscape of contemporary aesthetics in (...) Hungary, diversified by many fields of study, methods and subdisciplines. (shrink)

We consider a real-valued function f defined on the set of infinite branches X of a countably branching pruned tree T. The function f is said to be a limsup function if there is a function $u \colon T \to \mathbb {R}$ such that $f(x) = \limsup _{t \to \infty } u(x_{0},\dots,x_{t})$ for each $x \in X$. We study a game characterization of limsup functions, as well as a novel game characterization of functions of Baire class 1.

Somaesthetics and Sport (ed. Andrew Edgar, Brill, 2022) is a multifaceted collection of essays: Richard Shusterman’s theoretical framework is robust enough to lend unity to the volume, but it mostly functions as a springboard for the individual papers, never suffocating their theoretical explorations or making the book repetitive or a boring read. The ten essays also communicate with one another through certain recurring notions such as agency, somatic awareness, the Suitsian account of games or the interdisciplinary intertwining of philosophical arguments (...) with the results of sport psychology and physiology. Displaying the various ways Shusterman’s somaesthetics can be used to further the philosophical analysis of the aesthetic experience of watching and doing sports, the volume fills a gap in the scholarship of the aesthetics of sport as well as in the interdisciplinary field of somaesthetics. (shrink)

After decades of marginalization in the secularized twentieth-century academy, moral education has enjoyed a recent resurgence in American higher education, with the establishment of more than 100 ethics centers and programs on campuses across the country. Yet the idea that the university has a civic responsibility to teach its undergraduate students ethics and morality has been met with skepticism, suspicion, and even outright rejection from both inside and outside the academy. In this collection, renowned scholars of philosophy, politics, and religion (...) debate the role of ethics in the university, investigating whether universities should proactively cultivate morality and ethics, what teaching ethics entails, and what moral education should accomplish. The essays quickly open up to broader questions regarding the very purpose of a university education in modern society. Editors Elizabeth Kiss and J. Peter Euben survey the history of ethics in higher education, then engage with provocative recent writings by Stanley Fish in which he argues that universities should not be involved in moral education. Stanley Hauerwas responds, offering a theological perspective on the university’s purpose. Contributors look at the place of politics in moral education; suggest that increasingly diverse, multicultural student bodies are resources for the teaching of ethics; and show how the debate over civic education in public grade-schools provides valuable lessons for higher education. Others reflect on the virtues and character traits that a moral education should foster in students—such as honesty, tolerance, and integrity—and the ways that ethical training formally and informally happens on campuses today, from the classroom to the basketball court. _Debating Moral Education_ is a critical contribution to the ongoing discussion of the role and evolution of ethics education in the modern liberal arts university. _Contributors_. Lawrence Blum, Romand Coles, J. Peter Euben, Stanley Fish, Michael Allen Gillespie, Ruth W. Grant, Stanley Hauerwas, David A. Hoekema, Elizabeth Kiss, Patchen Markell, Susan Jane McWilliams, Wilson Carey McWilliams, J. Donald Moon, James Bernard Murphy, Noah Pickus, Julie A. Reuben, George Shulman, Elizabeth V. Spelman. (shrink)

The 18th-century emergence of aesthetics has been interpreted as a symptom of the entrance of a new image of man, individuality, a modern conception of subjectivity, a new mode of experience, as well as a new ideology or the modern concept of (fine) art into European consciousness. And even though these narratives all situate aesthetics within heteronomous contexts—from physiology and psychology to morality and politics, from social and economic history to belief and religion—one narrative came out as victorious, which neglects (...) the eighteenth-century interpenetration of various disciplines. It offers instead a teleological history of aesthetics which leads towards the concept of autonomy, aesthetic and/or artistic, as it takes shape, allegedly, in the aesthetics of Kant and then Romanticism. The new volume of the Routledge Studies in Eighteenth-Century Philosophy, entitled Beyond Autonomy in Eighteenth-Century British and German Aesthetics, joins the growing body of scholarship that re-examines the influential narratives of autonomy. (shrink)

Contemporary Complex Cinema. Complex conditions: the resurgence of narrative complexity ; Complex cinema as brain-candy for the empowered viewer ; Narrative taxonomies: simple, complex, puzzle plots -- Cognitive Approach to Contemporary Complex Cinema. Why an (embodied-)cognitive approach? ; Various forms of complexity and their effects on sense making ; Problematizing narrative linearity ; Complicating narrative structures and ontologies ; Under-stimulation and cognitive overload ; Contradictions and unreliabilities ; A cognitive approach to classifying complexity ; Deceptive unreliability and the twist film (...) ; Disorienting but solvable puzzle films ; Impossible puzzle films -- Narrative Complexity and Dissonant Cognitions. The concept of cognitive dissonance ; Cognitions in dissonance: from social psychology to narrative engagement ; Types of dissonance in narrative comprehension ; Narrative incongruities ; Narrative impossibilities ; Cognitive access to impossible storyworlds: immersed and reflected operations ; 'Impossibilities' and embodied cognition ; Disrupting viewers' reliance on image schemas by perceptual impossibility ; Disrupting viewers' reliance on image schemas by formal impossibility -- Taming Dissonance: Cognitive Operations and Interpretive Strategies. Cognitive dissonance versus narrative coherence ; Reducing dissonance: interpretation and naturalization ; Foregrounding ; Narrating agency and authorship ; Artefact emotions and metareflexive appreciation ; Interpretation as dissonance reduction ; Coping with dissonance: frame-switches and poetic and aesthetic readings ; Frame-switching as hermeneutic play in impossible puzzle films ; Switching between narrative and symbolical readings: Enemy and Mulholland Drive ; Cognitive hesitation and the fantastic -- Impossible Puzzle Films: Between Art-Cinema and (Post-) Classical Narration. From art-cinema to puzzle films ; Art-cinema as a narrative mode ; Dissonance in modernist art-cinema ; Art-cinema as a cognitive reception frame ; Narrative complexity and meaning-making in art-cinema ; Impossible puzzle films and (post-)classical narration ; High degree of tellability ; Identification with goal-oriented characters ; Strong reliance on classical genre elements ; Adherence to classical narrative cohesion devices ; Inclusion of quasi-rational frames of naturalization -- Wallowing in Dissonance: The Attractiveness of Impossible Puzzles. Hermeneutic play and interpretive multiplicity ; Orientation, navigation, mapping ; Game logic and the fascination in failure ; Effort justification ; Diegetization of decoupling ; Fascination in infinity ; Destabilized ontological certainty ; Eudaimonic motivations and intrinsic needs. (shrink)

Authors, especially “advocates for virtue,” writes Samuel Johnson in one of his Rambler essays, might consider following the example of monarchs, who, hiding themselves from the public, “avoid the conversation of mankind […], for men would not more patiently submit to be taught, than commanded, by one known to have the same follies and weaknesses with themselves.” It is easy to see, continues Dr. Johnson, that writing well is easier than living well: teaching navigation on land is not the same (...) as actually commanding a ship on sea, just as designing a life in “solitude, safety, and tranquility, with a mind unbiased, and with liberty unobstructed” is easier than actually living by that design “amidst tumult, and snares, and danger.” It is no surprise that allegedly even Milton was pleased that he did not disappoint an enthusiastic visitor and was “found equal to his own character”—a character born out of his textual world (Samuel Johnson, “The Rambler No. 14. (5 May, 1750)”, in Selected Essays from the Rambler, Adventurer, and Idler, ed. W.J. Bate. Yale University Press, 1968, 39, 40, 38). Johnson’s essay speaks of his deep insight into the chasm between the thinking, breathing, embodied self and contingent life of a writer and the textual self and models of life sculpted in her works. This insight, needless to say, has become a cliché in twentieth-century criticism, which dispensed with the naive view that literary discourse, including autobiographical works, is somehow transparent, a reflection of the writer’s self. For this reason, it might seem odd to look at literature from the perspective of a tradition that considers writing a crucial technique of examining and cultivating the self—something the ancient Greeks termed epimelesthai sautou, “the care of the self,” which was once understood to be the true goal of philosophy itself, conceived as the “art of living.” Richard Shusterman’s latest book, Philosophy and the Art of Writing revitalizes this ancient tradition of philosophy as an embodied way of living, and examines the various ways the process and product of the art of writing can contribute to the philosophical life dedicated to self-examination and self-improvement, while also pointing out the ambiguities of such an enterprise. (shrink)

A review of J. Colin McQuillan´s Early Modern Aesthetics.

Review of Journal of Scottish Thought. Volume 7. Francis Hutcheson and the Origins of the Aesthetic, ed. SZÉCSÉNYI ENDRE, The University of Aberdeen Press. 2016. pp. 212. £10.00.

Some people, we may call them realists, endorse the priority thesis. This thesis says political reasons have normative priority whenever we assess political situations. Any putative political reasons, I argue, must satisfy an autonomy condition and an identity condition. I argue that no realist account of political reasons shows such reasons are distinct and autonomous as of yet. One account, the practice-based account, may have the wherewithal to show political reasons are distinct. I also say some things about the relations (...) between identity, autonomy, and priority. (shrink)

Proceedings of the First Conference of the International Society for Hermeneutics and Science.

Duparc introduced a two-player game for a function f between zero-dimensional Polish spaces in which Player II has a winning strategy iff f is of Baire class 1. We generalize this result by defining a game for an arbitrary function f : X → Y between arbitrary Polish spaces such that Player II has a winning strategy in this game iff f is of Baire class 1. Using the strategy of Player II, we reprove a result concerning first return recoverable (...) functions. (shrink)

. Heuristic is a central concept of Lakatos' philosophy both in his early works and in his later work, the methodology of scientific research programs. The term itself, however, went through significant change of meaning. In this paper I study this change and the ‘metaphysical’ commitments behind it. In order to do so, I turn to his mathematical heuristic elaborated in Proofs and Refutations. I aim to show the dialogical character of mathematical knowledge in his account, which can open a (...) door to hermeneutic studies of mathematical practice. (shrink)

Sustainable development will shortly become the core issue of our everyday life. This article argues that only a nature-driven economy and society could give a final answer to sustainability questions.

IntroductionMentalizing is a key aspect of social cognition. Several researchers assume that mentalization has two systems, an explicit one and an implicit one. In schizophrenia, several studies have confirmed the deficit of explicit mentalizing, but little data are available on non-explicit mentalizing. However, increasing research activity can be detected recently in implicit mentalizing. The aim of this systematic review and meta-analysis is to summarize the existing results of implicit mentalizing in schizophreniaMethodsA systematic search was performed in four major databases: MEDLINE, (...) EMBASE, Cochrane Central Register of Controlled Trials, Web of Science. Eleven publications were selected. Five studies were found to be eligible for quantitative synthesis, and 9 studies were included in qualitative synthesis.ResultsThe meta-analysis revealed significantly lower accuracy, slower reaction time during implicit mentalizing in patients with schizophrenia. The systematic review found different brain activation pattern, further alterations in visual scanning, cue fixation, face looking time, and difficulties in perspective taking.DiscussionOverall, in addition to the deficit of explicit mentalization, implicit mentalization performance is also affected in schizophrenia, if not to the same extent. It seems likely that some elements of implicit mentalization might be relatively unaffected, but the effectiveness is limited by certain neurocognitive deficits. These alterations in implicit mentalizing can also have potential therapeutic consequences.Systematic Review Registration:https://www.crd.york.ac.uk/prospero/, identifier: CRD42021231312. (shrink)

The network concept is increasingly used for the description of complex systems. Here, we summarize key aspects of the evolvability and robustness of the hierarchical network set of macromolecules, cells, organisms and ecosystems. Listing the costs and benefits of cooperation as a necessary behaviour to build this network hierarchy, we outline the major hypothesis of the paper: the emergence of hierarchical complexity needs cooperation leading to the ageing (i.e. gradual deterioration) of the constituent networks. A stable environment develops cooperation leading (...) to over‐optimization, and forming an ‘always‐old’ network, which accumulates damage, and dies in an apoptosis‐like process. A rapidly changing environment develops competition forming a ‘forever‐young’ network, which may suffer an occasional over‐perturbation exhausting system resources, and causing death in a necrosis‐like process. Giving a number of examples we demonstrate how cooperation evokes the gradual accumulation of damage typical to ageing. Finally, we show how various forms of cooperation and consequent ageing emerge as key elements in all major steps of evolution from the formation of protocells to the establishment of the globalized, modern human society. (shrink)